The experts from DKMS and the DKMS Life Science Lab presented their research findings at the 34th annual meeting of the European Federation for Immunogenetics (EFI) which took place virtually from April 21 – 23, 2021.

Work by DKMS researchers covered topics from the fields of genotyping, population genetics, bioinformatics, and quality management.

Please find an overview of the talks and posters we presented at the EFI Congress 2021 below (speakers/presenters in bold):

Presentations

• Estimating HLA Haplotypes from homozygous individuals
  Susanne Seitz, Vinzenz Lange, Paul J. Norman, Jürgen Sauter, Alexander H. Schmidt
  Link to oral presentation: https://efi.talkingslideshd.com/view?presentation=12902
  (registered EFI participants only)
• Characterization of More Than 150 Novel HLA-E Alleles
  Christin Paech, Viviane Albrecht, Kathrin Putke, Bianca Schöne, Alexander H. Schmidt, Vinzenz Lange, Anja Klussmeier
  Link to oral presentation: https://efi.talkingslideshd.com/view?presentation=12912
  (registered EFI participants only)
• kTypeR – Accurate and Efficient Alignment-Free HLA Genotyping using Nanopore Sequencing
  Steffen Klasberg, Kathrin Putke, Markus Fuhrmann, Vineeth Surendranath, Alexander H. Schmidt, Vinzenz Lange, Gerhard Schöfl
  Link to oral presentation: https://efi.talkingslideshd.com/view?presentation=12901
  (registered EFI participants only)

Posters

Complementing the IPD-IMGT/HLA database by Complete Genomic Characterization of Non-Rare HLA-DRB1 Alleles
Viviane Albrecht, Christin Paech, Kathrin Putke, Madlen Pahlke, Steffen Klasberg , Gerhard Schöfl , Bianca Schöne, Alexander H. Schmidt, Vinzenz Lange , Anja Klussmeier

The Wipe Test Revolution: Introduction of a Sequencing Based Wipe Test in a High-Throughput Genotyping Laboratory
Kathrin Putke, Luise Birnstein , Claudia Gleitz , Manuela Münch , Lisa Müller , Alexander H. Schmidt, Vinzenz Lange, Anja Klussmeier

High-Throughput Genotyping of HLA-DRB3, -DRB4, -DRB5, -DQA1, and -DPA1 by Next Generation Sequencing
Isabell Schau, Julia Phieler, Kathrin Putke, Madlen Pahlke, Annett Mölle, Steffen Klasberg, Katharina Daniel, Lisa Müller, Andrea Heerde, Manuela Münch, Dominique Wittke, Nicole Dietel, Jana Heider, Anja Klussmeier, Jens Pruschke, Daniel Schefzyk, Jan A. Hofmann, Jürgen Sauter, Alexander H. Schmidt, Vinzenz Lange

Next Generation Sequencing based genotyping of HLA-DRB3, -DRB4, -DRB5, -DQA1, and -DPA1: the algorithmic aspect
Jens Pruschke, Daniel Schefzyk, Katharina Daniel, Isabell Schau, Kathrin Putke, Steffen Klasberg, Alexander H. Schmidt, Jan A. Hofmann, Vinzenz Lange, Jürgen Sauter

Graphical user interface for the haplotype frequency estimation software Hapl-o-Mat
Ute V. Solloch, Alexander H. Schmidt, Jürgen Sauter

Estimation of high-resolution 11-locus haplotype and allele frequencies based on 88,698 German potential stem cell donors
Susanne Seitz, Alexander H. Schmidt, Vinzenz Lange, Jürgen Sauter