Welcome to the educational video series designed for physicians and nurses with an interest in hematopoietic stem cell transplantation in the context of pediatric care for hemoglobinopathies and other non-malignant disorders in resource-limited settings. These videos feature two renowned experts in the field of stem cell transplantation, who consult the DKMS Access to Transplantation program and generously share their wealth of knowledge and experience: Dr. Lawrence Faulkner, Pediatric Hematologist-Oncologist and Bone Marrow Transplant Specialist (Cure2Children Foundation, Florence, Italy) and Dr. Ali Suliman, Assistant Member Bone Marrow Transplant and Cellular Therapy (St. Jude Children’s Research Hospital, Memphis, USA). Additionally, Sandeep, an experienced Bone Marrow Transplant Nurse from India, shares his knowledge.

The videos provide valuable insights into essential core competencies as defined by FACT/JACIE standards, with the aim of equipping healthcare professionals with the expertise needed to navigate the unique challenges posed by low-resource environments.

Whether you are an experienced nurse, practitioner or a medical professional eager to expand your understanding of stem cell transplantation, these videos offer a comprehensive and practical resource to enhance your skills.

1. The basics of hematopoietic stem cell transplantation
2. Quality assurance and outcome evaluation
3. Donor and recipient evaluation
4. Human leukocyte antigen (HLA) typing and ABO incompatibility management (to follow)
5. Marrow harvest procedure and marrow infusion
6. Central line management and infection control
7. Treatment plan, administration of preparative regimen, mucositis, vomiting and pain
8. Management of neutropenic fever and fungal disease
9. Blood product administration, thrombocytopenia and bleeding including hemorrhagic cystitis
10. Engraftment syndrome, sinusoidal obstruction syndrome and thrombotic microangiopathy
11. CMV activation and pulmonary complications
12. Acute and chronic graft-versus-host-disease

1. The basics of hematopoietic stem cell transplantation

2. Quality assurance and outcome evaluation

3. Donor and recipient evaluation

5. Bone marrow harvest procedure and marrow infusion

6. Central line management and infection control

7. Treatment plan, administration of preparative regimen, mucositis, vomiting and pain

8. Management of neutropenic fever and fungal disease

9. Blood product administration, thrombocytopenia and bleeding including hemorrhagic cystitis

10. Engraftment syndrome, sinusoidal obstruction syndrome and thrombotic microangiopathy

11. CMV activation and pulmonary complications

12. Acute and chronic graft-versus-host-disease

Last updated: 23.05.2024